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In this study, second-generation e-cigarettes were used, eliciting similar circulating nicotine concentrations to combustible tobacco, suggesting that other non-nicotine elements may be the primary cause of vascular dysfunction [116]

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Securities and Exchange Commission ("SEC"), including the Annual Report on Form 20-F and Current Reports on Form 6-K, which may be obtained free of charge at the SEC's website, and BAT's Annual Reports, which may be obtained free of charge from the British American Tobacco website www.bat.com

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