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Nicotine is a toxin that is present in tobacco plants and leaves in any form.[41] Public health research has shown that tobacco workers absorb nicotine through their skin while handling tobacco.[42] Studies have found that non-smoking adult tobacco workers have similar levels of nicotine in their bodies as smokers in the general population.[43] In the short-term, absorption of nicotine through the skin can lead to acute nicotine poisoning, called Green Tobacco Sickness, an occupational health risk specific to tobacco farming

You cannot opt out of the air you breathe

The figure indicates whether exercise, drugs, or both are effective treatments for each health condition listed

Volkow ND, Chang L, Wang GJ, Fowler JS, Ding YS, Sedler M et al (2001)

However, this is a cross-sectional study that cannot explain the effect of ECs on smoking cessation, and there is the limitation that the UCC alone is not sufficient to assess health risks