Therefore, we could not show which happens first: smoking dependence or depression among daily smokers, says Professor and Research Director Jaakko Kaprio from the University of Helsinki
It's also a major reason why trust in our public health officials is at an all-time low," PPT Director Michael Chamberlain said
One study suggests microglial activation as a result of developmental exposure, but this may not reflect chronic use in adults (Zelikoff et al., 2018)
We would recommend either varenicline or combination nicotine-replacement therapy as a first-line treatment, given their similar efficacy and good safety profiles in patients with stable mental health status
Chang SS, Jiang WW, Smith I, Glazer C, Sun W-Y, Mithani S, et al: Chronic cigarette smoke extract treatment selects for apoptotic dysfunction and mitochondrial mutations in minimally transformed oral keratinocytes