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Abbreviations AP-1: Activator protein-1 ALI: Airliquid interface AhR: Aryl hydrocarbon receptor ChIP-seq: Chromatin immunoprecipitation sequencing COPD: Chronic obstructive pulmonary disease CS: Cigarette smoke DEG: Differentially expressed gene FDR: False discovery rate FC: Fold change GSVA: Gene set variation analysis IEG: Immediate early gene CPM: Counts per million NNLS: Non-negative least squares Nrf2: Nuclear factor erythroid 2-related factor 2 PAH: Polycyclic aromatic hydrocarbons PBEC: Primary bronchial epithelial cells ROS: Reactive oxygen species SD: Standard deviation SVR: Support vector regression UMAP: Uniform manifold approximation and projection References Laniado-Laborn R

Incapsula incident ID: 1848000730129006904-52714839574319724

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In the latter two conditions, a distinct pattern has emerged: individuals often develop either NDDs or cancer, but rarely both

Good thing it can still be removed with the use of dental tools, tooth whitening products, and other oral care routines that you have to enforce without going to the dentist