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MFGM components can also act as bioactive compounds: Sphingolipids are a special kind of lipids that play an integral part in cell membrane structure and make up about 25% of the myelin sheath in neural cells

(76) showed in primary cultures of bovine parathyroid cells, maintained in short-term culture, that these cells underwent significant increases both in number and size in response to fetal calf serum, and that the addition of 10-100 ng/mL calcitriol almost completely inhibited cell proliferation whereas cell hypertrophy was unaffected

Funding This study was supported by grants from the Danish Council for Independent Research (6110-00660), the Lundbeck Foundation (2011-9560, 2016-2394), the European Foundation for the Study of Diabetes (EFSDLilly Young Investigator Research Award 2019), and the Novo Nordisk Foundation

Physiol J 2014