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The minimum sample size was determined using the Raosoft online sample size calculator with a 0.1 margin of error, a 95% confidence level, and a reported prevalence of cardiometabolic risk of 39.8% in the Saudi population 26

These long and thin cigars are known for their complex flavors that develop throughout the smoke

Levels of chromium, nickel and antimony increased as the number of puffs increased

Twenty-five percent of the study participants had ever smoked, with 11 % daily, and half of them had been heavy smokers (10 cigarettes per day)

To evaluate the robustness of the findings, leave-one-out sensitivity analyses (involving the systematic exclusion of one SNP at a time) were performed 28