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Amanda Velazquez and patients from around the country who have a range of personal experiences with prescription weight loss medications, including a teenager who was among the first to take the new drugs and begs the question whether these medications should be given to minors
Secondary Outcome: Secondary Outcomes: Changes in waist circumference, body fat, body lean mass, and metabolic risk factors including levels of plasma glucose, insulin sensitivity, serum lipids, and blood pressure Statistical Analysis Full details previously published 2 and can also be found in the STEP group statistical analysis plan at NEJM.org Statistical analysis approach sought strong control for type I error All endpoints addressing intervention efficacy were analyzed using intention-to-treat approach All endpoints addressing intervention safety were analyzed using per-protocol approach Efficacy endpoints analyzed using 2 estimands Treatment Policy Estimand: intention to treat analysis
It is prescribed for individuals with type 2 diabetes to help keep blood sugar in check, and for people who are looking to lose weight when other methods havent worked well
12.31.19 2019 year-end total adverse events 1,244 total cases, including 22 deaths
Units = (2.4 / 2.5) x 100 = 96 units
