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Decreased levels of other cytokines and modulators namely interleukins (IL-2, IL-6), granulocyte/macrophage-colony-stimulating factor (GM-CSF) and macrophage chemotactic protein 1 (MCP-1) are also seen (89)

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Thus, ROS plays an important role in the alteration and maintenance of M1/M2 polarization, as well as macrophages corresponding functions

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