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That was the beginning of the end. They also appealed to companies bottom lines: smokers take a lot of breaks, damage equipment and often get seriously sick

"95% less" represents the average reductions in levels of a range of harmful chemicals (excluding nicotine) compared to the smoke of a reference cigarette

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E6 promotes degradation of the tumor suppressor p53, disrupting genomic surveillance and indirectly promoting DNMT upregulation, leading to aberrant DNA methylation patterns