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Noncombustible tobacco products are often viewed as clean nicotine delivery systems and considered less harmful than cigarettes, leading some to advocate for their use in smoking cessation

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Several gene families of interest were investigated (Fig 4A), based on criteria of being both present, and of medical importance, or with the potential for harm in the product (based on pro-inflammatory properties)

for ischemic heart disease are used, the overall AM increases by 26.5%, with an estimated 945 (95% CI 8561039) deaths attributable to ETS exposure, albeit with an increase in ischemic heart disease-AM and a decrease in lung cancer-AM

S., Hardie, J