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While Tolkien's own habit was likely an inspiration for the Hobbits' beloved herb, this quote also creates room for interpretation by saying, "a variety probably of Nicotiana" The "probably" suggests pipe-weed could be another type of "herb," like marijuana

The chemicals build up and cause damage

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I was a Kodiak Wintergreen guy so this is right up my alley, but if you were a Cope or Skoal flavored (Cherry, Mint, Straight, etc.) dipper you may not like this flavor

Now there are new shaped tins, similar to an Altoid mint box, that contain nicotine filled mints that are being marketed towards the younger crowd, typically children ages 11-13