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While our analyses adjusted for several major conditions including diabetes and cardiovascular diseases, we acknowledge that residual confounding from unmeasured or subclinical inflammatory sources cannot be fully excluded

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Antibody serology testing for HSV in low-prevalence groups produces a meaningful number of false positives, and a false-positive herpes diagnosis carries real psychological and relational cost

The devices are currently produced at a pilot factory in Bologna, Italy, but if it proves successful in its test markets, Phillip Morris plans to build a larger one capable of producing up to 30 billion HeatSticks per year

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