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Clinicians who treat smokers diagnosed with ILDs are managing a condition which could have been a result of cigarette use and moreover worsened by smoking

This framework evaluates several key aspects: biological plausibility (i.e., whether the upstream and downstream events are mechanistically linked), the essentiality of key events (i.e., whether blocking an upstream KE prevents the occurrence of downstream events), empirical support (i.e., consistency with doseresponse, temporal, and incidence patterns), and overall coherence across studies ( In this study, KERs were evaluated through an automated, literature-based approach using the eventevent module of AOP-helpFinder

I found some samples of this at Goodwill and don't know how old they are so I'm not sure what version it is

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