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Journal Of The American College Of Cardiology 2021, 78: 2161-2172

Moreover, recent study found that hypoxia-inducible factor (HIF)1 and HIF-2 in GBM cells jointly mediate upregulation of the mRNA and protein expression levels of the BCAAs transporter LAT 1 and the BCAAs metabolizing enzyme BCAT1, and ultimately promote the growth of cells under hypoxia conditions

Transcriptomic advances in studies of muscle stem cell aging: From bulk to single-cell and beyond

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However, only the high molecular weight (HMW) complexes of At APX1 and Os APX2 display chaperone activity, whereas the LMW forms exhibit predominantly PRX activity (Hong et al