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Conversely, concomitant use of nicotine and rifabutin, a CYP2B6 inducer, will result in a modest increase in mediated metabolism of the substrate, potentially leading to a reduction in serum concentration and/or therapeutic effect (DrugBank Clinical API Plugins, 2024)

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uvres, 1898

If The Tobacco and Vapes Bill, as it is formally called, goes ahead it will raise the age a person can legally buy tobacco from the current 18 by one year annually

18 Stopping NRT