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Moreover, e-cigarette use significantly reduces lung function in asthma patients (reduced FEV 1 /FVC ratio and peak expiratory flow (PEF)), and increases the fraction of exhaled nitric oxide (FeNO) and the pH of exhaled breath condensate (EBC) by 3.60 ppb ( p = 0.001) and 0.15 ( p = 0.014), respectively [75]

It is important to note that, in contrast to nuclear organelles, mitochondria are the only non-nuclear organelles that possess their own genome

Current smoking with or without chronic bronchitis is independently associated with goblet cell hyperplasia in healthy smokers and COPD subjects