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Similarly, patients with sepsis often develop sepsis-associated encephalopathy (SAE), a condition characterized by altered mental status and long-term cognitive impairments

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Start: 2.5 mg once weekly for 4 weeks (initiation dose) [1]

Recent work suggests an interaction with the JAK-2/STAT-3 pathway, involved in the inflammatory response and cell survival, reinforcing the hypothesis of a pleiotropic mechanism of action