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Manufacturers recommend keeping vape devices in an upright position when not in use to avoid the device leaking e-liquid

While at the inception of the Lotus Project, pouch products' users were expected to graduate to the higher nicotine brands of loose MST, Skoal and Copenhagen, [13, 33] over time pouch product variants of higher nicotine MST have also been introduced, including large size pouches of Skoal, Grizzly, and Copenhagen (Table 1)

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There can be no doubt that JUULs aggressive advertising has significantly contributed to the public health crisis that has left youth

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