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Although we adopted a quantitative approach to infer behavioral relevance of structural alterations, we note that our interpretations remain largely speculative until experimentally verified

One study looked at the effects of smokeless tobacco on the oral microbiome of healthy adults and those with oral squamous cell carcinoma and found a high prevalence of Streptococcus, Prevotella, and Fusobacterium in the oral flora of smokeless tobacco users [3]

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Female smokers were more likely than male smokers to develop these diseases, regardless of the number of cigarettes smoked