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Big tobacco companies like Altria, however, engineered the MSA to their benefit by making it more difficult for smaller companies to enter the market and compete on price

For some, it may take a longer period of abstinence to feel motivated to make an additional change

However, because a causal effect can exist in the absence of supporting ecological or analogous evidence due to potential methodological or conceptual limitations that restrict causal inferences from such studies, causal conclusions could be made in the presence of inconsistent evidence across epidemiological studies and these additional forms of evidence

Evidence of the benefits of e-cigs in aiding smoking cessation is at best theoretical with no definitive evidence

Little is known about how the manufacturing, use and disposal of e-cigarettes affect the environment, according to an FDA/Center for Tobacco Products literature review