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[35] [36] By the mid-17th century, most major civilizations had been introduced to tobacco smoking and, in many cases, had already assimilated it into the native culture, despite some continued attempts on the part of rulers to eliminate the practice with penalties or fines

Not always, because local laws vary

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More research is needed to determine whether this results from the drug itself or from other lifestyle factors among those who choose to use cannabis while they are pregnant, Solmi says