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Their effects on the individual components of MACE, myocardial infarction (reduced in LEADER and Harmony Outcomes), and stroke (reduced in SUSTAIN-6 and REWIND), varied in each trial (Table 1)
Results and safety may vary depending on individual factors, including genetics, lifestyle, and overall health.
P., Wu, Q., Du, Y., Gurbuz, S., & Hartman, M
Behavioral: Changes in appetite (decreased) have been reported
In July 2024, a retrospective study on overweight or obese adults treated for type 2 diabetes, 81.8% of people receiving tirzepatide (Mounjaro) lost at least 5% of their weight within one year compared to 66.5% of those using semaglutide (Ozempic), a significant difference (which means it did not just happen by chance)
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