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Indirect pathways include UV radiation-induced changes in the action of cytokines and other mediators of the immune response, such as nitric oxide, cis -urocanic acid, ligands of the aryl hydrocarbon receptor, platelet-activating factor (PAF), prostaglandin E2, anti-microbial peptides, and vitamin D [13]

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Behavioural Substitutions The hand-to-mouth action of vaping satisfies both oral fixation and habitual movement patterns

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