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Practical Application Reduce processed foods: Minimize refined carbs, trans fats, excessive omega-6 Emphasize whole foods: Vegetables, fruits, whole grains, lean proteins Stress management: Meditation, yoga, deep breathing reduces inflammatory signaling Adequate vitamin D: Low vitamin D correlates with elevated DPP-4 Colorful vegetables: Rich in polyphenols that modulate inflammation Berries: High anthocyanin content supports metabolic health Nuts and seeds: Provide healthy fats and anti-inflammatory compounds Green tea: Dual benefit of DPP-4 inhibition and anti-inflammatory effects Combining Strategies: A Comprehensive DPP-4 Management Plan Individual strategies provide modest DPP-4 modulation

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We performed additional analyses of treatment discontinuation and reinitiation in which we used grace periods of 60, 180 and 365 days

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Schwartz AR, Patil SP, Laffan AM, et al