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But their long-term effects are unknown, and if they turn out to be bad, those effects will likely be worst for the people who started vaping young

Furthermore, studies using diet-induced models of MASLD have shown that e-cigarette exposure exacerbates preexisting liver injury, worsening steatohepatitis through amplified oxidative stress, mitochondrial dysfunction, and inflammatory responses [134]

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Interestingly, these changes worsened after quitting smoking, with a drop in sex hormone-binding globulin (SHBG) noted as early as the first week of non-smoking

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