For a 60-year-old living with type 2 diabetes, who has already had a cardiovascular event, previous studies estimate that life expectancy could be reduced by up to 12 years compared with someone of the same age without these conditions, commented Brian Claggett, Ph.D., Division of Cardiovascular Medicine, Brigham and Womens Hospital and lead author of the Circulation paper
[3-5],[60-65] The most common side effects of GLP-1RA are gastrointestinal (nausea, vomiting, diarrhea)
Analysis of fecal samples suggests that the gut microbial communities of obese individuals taking cholesterol-lowering statin medications are healthier than expected, suggesting that the potential beneficial effects of statins on gut microbiota open up new prospects for disease treatment (Vieira-Silva et al., 2020)
Rotating injection sites and proper technique minimize this
More recently, researchers have applied these findings to the emerging crisis of Long COVID