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The annual medical costs for migraine in China amount to 331.7 billion, causing significant economic losses and severely affecting the quality of life for patients (Yu et al., 2011)
With respect to GPx-1 in hypertension, our own study was the first clinical evidence (9) to shed light on the notion that the relationship between the level of antioxidants including GPx-1 and clinical pathologies is not always straightforward and that the protective role of increased activities of antioxidant enzymes depends on other factors including the characteristics of the oxidative milieu
Meanwhile, the presence of PD-L1 on T cells may also interact with CD80 on APCs (214) leading to tumor-promoting tolerance through varying mechanisms (207)
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Additionally, compared to conventional methods, supercritical fluid extraction protects bioactive compounds from air and light, reducing degradation and minimizing contamination risk from impure solvents (57)
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