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Practice 10 minutes of 4-7-8 breathing (inhale 4 counts, hold 7, exhale 8) twice daily, ideally before meals, to activate the vagus nerve and restore the parasympathetic state that allows gut immune function to operate at full capacity

At 72 weeks, mean weight loss was 15.0% (5mg), 19.5% (10mg), and 22.5% (15mg) versus 3.1% with placebo

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Unlike sterile water for injection, which is intended for single-use only and must be discarded after the seal is broken, bacteriostatic water can be safely used multiple times over a period of up to 28 days after initial puncture