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As a dual agonist, tirzepatide has demonstrated superior efficacy compared to selective GLP-1 receptor agonists in both glycemic control and weight reduction

Persistent Metabolic Adaptation The body may still be operating at a reduced energy expenditure level from prior weight loss

Patients with higher baseline BMI given higher doses of dulaglutide experienced the most weight loss

However, be aware that high-dose corticosteroids temporarily raise blood sugar levels, which may offset some of Wegovys glucose-lowering effects

Gentle swirling rather than vigorous shaking is important to avoid damaging the peptide structure