The scoring standard for IHC staining adopted the immunoreactive score (IRS) system [15, 16], with the specific rules as follows: the staining intensity of GGCT protein was classified into four grades, where a score of 0 indicated no staining signal, 1 indicated weak positivity, 2 indicated moderate positivity, and 3 indicated strong positivity
1.25.20 15mins said: Theres one in the comments above from this month
Acknowledgements This project was supported by the National Natural Science Foundation of China (82272232, 82170775, 82370765, 82270802, 82100806, and 82300766) and the Open Project of Hubei Key Laboratory (2023KFZZ009)
This oxidative damage is evidenced by elevated levels of 8-hydroxydeoxyguanosine, indicating compromised DNA integrity that facilitates mutations in melanoma-related genes like BRAF and loss of tumor-suppressor functions 119
Minich DM et al