why am i not losing weight on semaglutide reddit feeling like I'm fast enough : r/Semaglutide How am I not losing

Chronic exposure to GLP-1R agonists promotes homologous GLP-1 receptor desensitization in vitro but does not attenuate GLP-1R-dependent glucose homeostasis in vivo

The injection costs $299 to $399 per month, again, depending on the dose

Studies using dual-energy X-ray absorptiometry (DXA) demonstrate reductions in total fat mass up to 10.9 kg, with particular effectiveness in reducing visceral fatthe metabolically harmful abdominal fat strongly associated with cardiovascular and metabolic disease risk

Drugs@FDA: FDA-Approved drugs [Internet]

Maybe a combined approach, where you're reducing the pain through weight management, but you're also trying to regenerate the cartilage, is the way to go in the future.