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While low levels of ROS are necessary for normal sperm functions such as maturation and fertilization, excessive ROS accumulationdriven by conditions like varicoceles, infections, or exposure to tobacco, alcohol, radiation, and environmental toxinscan lead to significant sperm damage

Role of quercetin (a natural herbal compound) in allergy and inflammation

The CLOCK/BMAL1 heterodimer combines with the E-box response element which located in the promoter region to stimulate the expression of other target genes, the core of which is the transcriptional expression of other clock genes, such as Periods ( PER1 , PER2 , and PER3 ), and Cryptochromes ( CRY1 and CRY2 )