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Propranolol and low-dose isoproterenol ameliorate insulin resistance, enhance beta-arrestin2 signaling, and reduce cardiac remodeling in high-fructose, high-fat diet-fed mice: Comparative study with metformin

Polyphyllin D can combate drug resistance by stimulating hypertrophied lysosomes targeting acidic sphingomyelinase (SMPD1) in liver cancer

The peptide protects gastric mucosa from damage induced by NSAIDs (non-steroidal anti-inflammatory drugs), alcohol, and stress, counteracting the pathological effects of these ulcerogenic agents

Detecting disease before it progresses may allow intervention to have the greatest effect (Rosner 2006)