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If you've had a BAD experience with B12 shots, it's most likely that you do not tolerate or convert cyanocobalamin well (see if you can verify what form of B12 was in the shot that made you react poorly, and then stay away from that specific form if you can)

These include safeguarding cells against oxidative damage, facilitating amino acid transport, detoxifying foreign compounds, maintaining protein sulfhydryl groups in a reduced state, and acting as a cofactor for numerous enzymes

These custom-mixed versions are not FDA-approved for safety and may use different, unproven salt forms of the drug