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By serving as an immediate treatment option that reduces addictive drive without precipitating withdrawal symptoms, GLP-1 supported initiation onto buprenorphine and naltrexone may improve success rates by making it easier for patients to reach the short-term withdrawal thresholds required to begin treatment

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This personalization prevents the trial-and-error prescribing that often leads patients to request multiple medications

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A push-pull mechanism for heterolytic O-O bond cleavage in hydroperoxo manganese porphyrins