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Fulcher KD, Welch JE, Klapper DG et al (1995) Identification of a unique -class glutathione S-transferase in mouse spermatogenic cells

If nighttime dosing is not possible, an early morning dose may be suitable

This observation remains anecdotal but appears consistently across user reports

As the field develops, direct measurement of circulating MOTS-c may become a useful biomarker for guiding dose adjustments, similar to how IGF-1 is used to monitor growth hormone or testosterone levels guide TRT dosing

D., Cai, X., Ma, C., Wang, Y., Dai, A., Zhou, Y., Sun, W., Zhao, F., Zhao, S., Jiang, H., Jiang, Y., Yang, D., Eric Xu, H., Wang, M