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GPX4 is a key antioxidant enzyme responsible for reducing harmful LPO to harmless lipid alcohols so as to protect cells against oxidative damage

Dysesthesia In a pool of Study 1 and 2, dysesthesia occurred more frequently among patients receiving ZEPBOUND (5 mg 0.2%, 10 mg 0.2%, 15 mg 0.4%) than placebo (0.1%)

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doi: 10.5114/ADA.2017.71110 168 Dalle-DonneIAldiniGCariniMColomboRRossiRMilzaniA

Good news for Lilly investors, frustrating news for patient accessibility and affordability