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Although this form of thiamine deficiency, which we call gastrointestinal beriberi, is initially limited to the gastrointestinal system, it mostly progresses to systemic thiamine deficiency, often triggered by stresses of different etiologies

Safety and regulatory status vary: some are FDA-approved for sexual disorders or metabolic indications, while others are off-label or investigational

But because the gut is leaking toxins, the immune system is hyperactivated, consuming all available L-Glutamine in the bloodstream

doi: 10.1042/0264-6021:3600557 95 GheorghiuMLBadiuC

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