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Surface modification of iron oxide-based magnetic nanoparticles for cerebral theranostics: application and prospection

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The accumulation of reactive oxygen species (ROS), a hallmark of oxidative stress, serves a key role in initiating ferroptosis

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Currently, in vivo brain markers in AD and MCI mainly include positron emission tomography scanning of amyloid, tau, and glucose metabolism, as well as brain structural imaging using MRI such as hippocampal atrophy [81]