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[DOI] [PMC free article] [PubMed] [Google Scholar] 302.Elikaei A, Vazini H, Javani F

10.1016/j.chemosphere.2010.10.070 Chemosphere 68 ReymondP.WeberH.DamondM.FarmerE

The administration of 300 mg of coenzyme Q 10 12 hours before the angioplasty to 50 patients reduced the concentration of C-reactive protein ([CRP]

But you've reduced effective dose by nearly half through timing alone

Neuroscience 26(277):747754 Paudel YN, Angelopoulou E, Piperi C, Shaikh MF, Othman I (2020) Emerging neuroprotective effect of metformin in Parkinsons disease: a molecular crosstalk