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Thus, in deploying APAP as a therapeutic option, one must account for both age-dependent differences in the PK/PD of APAP and the inter-patient variability within the pediatric population itself

Variations in human population compared to animals Since errors of measurement in samples from individuals are relatively small (CV = 13 % across triplicate, independently processed samples), the large observed inter-individual range (GSH, CV = 37 %

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