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Compound structures were retrieved from the PubChem database in SMILES format, converted to 3D conformations with RDKit (v2025.03.26), and further energy-minimized with the MMFF94 force field
Besides, betalains in beetroot have also been shown to inhibit oxidative metabolism of neutrophils in humans (ZieliskaPrzyjemska et al., 2009), enhance the activity of the antioxidant enzymes, superoxide dismutase, and peroxidase in irradiated mice liver, spleen, and kidney (Wroblewska et al., 2011)
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Mitochondrial oxidative stress and respiratory dysfunctions in cancer cells may, therefore, lead to the activation of apoptotic signals by the release of apoptosis-inducing factors and proteins and subsequent activation of the caspases [17], [18], [19]
Levels of three oxidative stress biomarkers, conjugated dienes, lipid hydroperoxide and thiobarabituric acid were determined in preovulatory follicles
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