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In some embodiments, the otic formulation or composition comprises between about 0.01% to about 7% by weight of the therapeutic agent, or pharmaceutically acceptable prodrug or salt thereof

The prescription cascade, where new medications are added to treat the adverse effects of other medicationsfurther exacerbates the problem (9-10)

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You should rotate between approved injection sites (abdomen, thigh, upper arm) and move each injection at least 2.5 cm from the previous spot to prevent lipohypertrophy and tissue damage