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VEGF is the primary mediator of blood vessel growth

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With its excellent safety profile and ease of administration, epithalon may be administered twice annually in two short courses for its geroprotective effects

Advances in Gerontology, 1 , 328-339

However, efforts must also focus on the interim strategy to slow neuron losses in brain structures impacted including neocortices, hippocampus, locus ceruleus and the nucleus basalis of Meynert by stimulating synaptogenesis, neurogenesis and reducing neuroinflammation and oxidative stress