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J Ovarian Res 17:27 Murri M, Luque-Ramrez M, Insenser M, Ojeda-Ojeda M, Escobar-Morreale HF (2013) Circulating markers of oxidative stress in PCOS: a systematic review and meta-analysis

In fact, piretanide (Harno et al., 1985) and likely bumetanide (Harno et al., 1985) increased insulin secretion in humans

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In the CNS, GSH is synthesized primarily by astrocytes and transported to neurons, where it provides oxidative resistance (Dringen and Arend, 2025)