Selenium deficiency decreases the activity of selenoproteins, including glutathione peroxidases, which can lead to raised concentrations of hydrogen peroxide and thus promote inflammation and disease
On a chow diet, adipocyte-specific loss of Bmal1 impaired glucose tolerance and caused compensatory hyperinsulinaemia, which was normalized by NDI1 (Extended Data Fig
Supplementing with vitamin B12 is particularly common, because deficiency is widespread
It arises from fat-storing perisinusoidal cells, better known as Ito cells (Dixon et al
Biochemical analyses were performed on maternal serum, fetal brains, and adult prefrontal cortex, measuring IL-6 and IL-17a (ELISA), parvalbumin-positive interneurons (immunofluorescence), and GABA/glutamate levels (HPLC)