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Probiotics for gastrointestinal symptoms and quality of life in autism: a placebo-controlled pilot trial
They recruited 20 men, cannulated them (inserted IV lines for blood sampling), gave them a fixed-energy meal to standardize gut hormones, then administered the hop extract in a delayed-release capsule targeting the upper small intestine one hour before an eat-until-full meal, followed by an eat-until-full snack two hours later
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Because GLP-1 medications slow gastrointestinal motility, the incidence of constipation may increase [16, 17]
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