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Its main job is mopping up free radicals, the unstable molecules that damage cells and speed aging

Reduced Glucagon Secretion : They suppress the release of glucagon, a hormone that raises blood sugar, further contributing to glucose control

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Using primary CLL cells classified as NOTCH1 wild-type (CLL/N WT ) or mutated (CLL/N M ), both with UM-BCR, we show that BCR stimulation activates the NOTCH1 pathway, upregulating metabolic programs and mitochondrial biogenesis, selectively in CLL/N M