These include people with a history of thyroid and some other cancers, those with kidney issues or pancreatitis, and those who are pregnant or breastfeeding
At a basic level, GLP-1 receptor agonists work in two well-established ways: They slow gastric emptying, and they act on the brains appetite-regulation centers to reduce food intake
Understanding Semaglutide Semaglutide is an FDA-approved GLP-1 receptor agonist targeted for adults with obesity or who are overweight with related health conditions such as diabetes
This conclusion should not be overlooked as a distraction factor with small sample size
Last reviewed: July 2, 2026 Last updated: July 2, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations