glp-1 with glycine Personalized backed formula is designed to support digestion and reduce common discomforts like bloating Risky off-brand GLP-1 drugs become

Researchers should be looking for key biofeedback markers to confirm the protocol is on track or if it's time for a break

Chang C, et al

None of the studies particularly caught our eyes this week, with one of the studies (paper two (2) ) being on the use of CBT in a range of chronic health conditions, with the introduction claiming that CBT is an evidence-based treatment for ME/CFS (which is against the new NICE guidelines advice)

The AMPK-ACC-CPT1 axis acts as a key regulatory node: AMPK activation phosphorylates ACC, reducing malonyl-CoA levels and relieving inhibition of CPT1 to enhance FAO and Treg differentiation (103)

The HFI series of compounds, e.g., 37 (HFI 419) identified in 2008 after the virtual screening are much more drug-like than the hexapeptides 11 (AL-11), 12 (IVDE77), and the potent macrocyclic Ang IV analogue 23 (HA08) and can hopefully after further systematic optimization be converted into bioactive small molecules with capacity to cross the blood-brain barrier